What is a potential complication if osteosarcoma is not treated?

• A. Lung metastasis
• B. Bone fracture
• C. Malnutrition
• D. Neurological damage

Answer: (A)

Osteosarcoma is a malignant bone tumor that is primarily found in adolescents and young adults. One of the hallmark features of osteosarcoma is its tendency to metastasize, particularly to the lungs. If osteosarcoma is not treated, the tumor can invade surrounding tissues and spread through the bloodstream or lymphatic system, leading to the formation of secondary tumors in the lungs. Lung metastasis is a severe complication because it can significantly affect respiratory function and overall prognosis for the patient, making effective treatment crucial for preventing this outcome.

Other potential complications, such as bone fracture, can occur due to the weakening of bone structure by the tumor itself, but pulmonary metastatic spread is a more dire consequence that directly affects the overall survival and quality of life. Malnutrition or neurological damage are not typical complications associated specifically with untreated osteosarcoma. For these reasons, the development of lung metastasis is recognized as a primary concern when dealing with untreated osteosarcoma.